Assay Detail

CHEMBL765297

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiviral activity against HIV-1 strain LAI in PBM cells on day 6

ChEMBL ↗

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Target

ADMET (CHEMBL612558) ↗

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Primary target ADMET

CHEMBL612558

Anchored from Assay target.

Protein identity ADMET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	PBM
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

ADMET (CHEMBL612558) ↗

Type

ADMET

Publication

Synthesis and biological properties of 5-o-carboranyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil.

Fulcrand-el Kattan G, Goudgaon NM, Ilksoy N, Huang JT, Watanabe KA, Sommadossi JP, Schinazi RF.
J Med Chem (1994) 37 : 2583 -2588
PubMed 8057301 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	5.14	5.14

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3142559	—	—	1	5.14

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3142559	—	EC50	=	7300.0	nM	5.14