Assay Detail
Binding
CHEMBL765856
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Compound was evaluated for inhibition of Prostaglandin G/H synthase 1
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The identification of cyclooxygenase-1 inhibitors from 4-thiazolidinone combinatorial libraries
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.20 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL164319 | — | — | 1 | 5.55 |
| CHEMBL101 | PHENYLBUTAZONE | 4.0 | 1 | 5.52 |
| CHEMBL423640 | — | — | 1 | 5.43 |
| CHEMBL521 | IBUPROFEN | 4.0 | 1 | 5.20 |
| CHEMBL351983 | — | — | 1 | 5.03 |
| CHEMBL345222 | — | — | 1 | 4.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL164319 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL101 | PHENYLBUTAZONE | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL423640 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL521 | IBUPROFEN | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL351983 | — | IC50 | = | 9400.0 | nM | 5.03 |
| CHEMBL345222 | — | IC50 | = | 34400.0 | nM | 4.46 |