Assay Detail
Binding
CHEMBL766127
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Compound was tested for inhibition of prostaglandin synthetase when administered perorally
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis and antiinflammatory activity of some 2-(substituted-pyridinyl)benzimidazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.47 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL101 | PHENYLBUTAZONE | 4.0 | 1 | 4.82 |
| CHEMBL162115 | — | — | 1 | 4.12 |
| CHEMBL538059 | TIARAMIDE HYDROCHLORIDE | -1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL101 | PHENYLBUTAZONE | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL162115 | — | IC50 | = | 76000.0 | nM | 4.12 |
| CHEMBL538059 | TIARAMIDE HYDROCHLORIDE | IC50 | > | 100000.0 | nM | - |