Assay Detail
Binding
CHEMBL766182
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Displacement of [3H]progesterone at progesterone receptor of T47D cells
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel pyrrole-containing progesterone receptor modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 8.04 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1276308 | MIFEPRISTONE | 4.0 | 1 | 9.15 |
| CHEMBL305298 | — | — | 1 | 8.47 |
| CHEMBL103 | PROGESTERONE | 4.0 | 1 | 8.47 |
| CHEMBL67860 | — | — | 1 | 8.31 |
| CHEMBL431380 | — | — | 1 | 8.03 |
| CHEMBL303209 | — | — | 1 | 7.75 |
| CHEMBL308938 | — | — | 1 | 7.60 |
| CHEMBL305946 | — | — | 1 | 7.54 |
| CHEMBL70114 | — | — | 1 | 7.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1276308 | MIFEPRISTONE | IC50 | = | 0.7 | nM | 9.15 |
| CHEMBL305298 | — | IC50 | = | 3.4 | nM | 8.47 |
| CHEMBL103 | PROGESTERONE | IC50 | = | 3.4 | nM | 8.47 |
| CHEMBL67860 | — | IC50 | = | 4.9 | nM | 8.31 |
| CHEMBL431380 | — | IC50 | = | 9.4 | nM | 8.03 |
| CHEMBL303209 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL308938 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL305946 | — | IC50 | = | 29.0 | nM | 7.54 |
| CHEMBL70114 | — | IC50 | = | 88.0 | nM | 7.06 |