Compound Detail
CHEMBL70114
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Basic Information
| ChEMBL ID | CHEMBL70114 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CMBBFWANSALAAB-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
281.3
MW (Da)
3.36
ALogP
4
HBA
1
HBD
67.0
PSA (Ų)
0.87
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.39
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Progesterone receptor CHEMBL208 | IC50 | 7.39 | 7.39 | 41.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 7.06 | 7.06 | 88.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Progesterone receptor | IC50 | = | 41.0 | nM | 7.39 | Ability to block progesterone induced alkaline phosphatase activity in T47D huma... | 15081005 |
| Unchecked | IC50 | = | 88.0 | nM | 7.06 | Displacement of [3H]progesterone at progesterone receptor of T47D cells | 15081005 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15081005 | 10.1016/j.bmcl.2004.02.054 | Progesterone receptor | 2 |
| 15081005 | 10.1016/j.bmcl.2004.02.054 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine