Assay Detail
Binding
CHEMBL766267
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bovine heart phosphodiesterase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Expert |
Publication
Synthesis and antibronchospastic activity of 8-alkoxy- and 8-(alkylamino)imidazo[1,2-a]pyrazines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.10 | 4.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL112904 | — | — | 1 | 4.16 |
| CHEMBL1355736 | THEOPHYLLINE | 4.0 | 1 | 4.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL112904 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL1355736 | THEOPHYLLINE | IC50 | = | 92000.0 | nM | 4.04 |