Assay Detail
Binding
CHEMBL766336
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In vitro for inhibition of plasmin
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
(N-acyl-N-alkyl)glycyl borolysine analogs: A new class of potent thrombin inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 6.64 | 8.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290376 | — | — | 1 | 8.29 |
| CHEMBL330206 | — | — | 1 | 6.85 |
| CHEMBL317137 | — | — | 1 | 6.80 |
| CHEMBL99309 | — | — | 1 | 6.77 |
| CHEMBL101759 | — | — | 1 | 6.64 |
| CHEMBL419892 | — | — | 1 | 6.60 |
| CHEMBL317682 | — | — | 1 | 6.60 |
| CHEMBL95940 | — | — | 1 | 6.34 |
| CHEMBL431814 | — | — | 1 | 4.85 |
| CHEMBL95993 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290376 | — | Ki | = | 5.1 | nM | 8.29 |
| CHEMBL330206 | — | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL317137 | — | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL99309 | — | Ki | = | 170.0 | nM | 6.77 |
| CHEMBL101759 | — | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL419892 | — | Ki | = | 250.0 | nM | 6.60 |
| CHEMBL317682 | — | Ki | = | 250.0 | nM | 6.60 |
| CHEMBL95940 | — | Ki | = | 460.0 | nM | 6.34 |
| CHEMBL431814 | — | Ki | = | 14000.0 | nM | 4.85 |
| CHEMBL95993 | — | Ki | > | 10000.0 | nM | - |