Assay Detail
Binding
CHEMBL766693
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for inhibitory concentration of Protein Phosphatase 2A (PP2A).
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (CHEMBL3557) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Inhibition of protein phosphatase 2A by cantharidin analogues
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.55 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8066 | — | — | 1 | 5.10 |
| CHEMBL273883 | — | — | 1 | 4.40 |
| CHEMBL8327 | DEMETHYL-CANTHARIDIN | — | 1 | 4.16 |
| CHEMBL8157 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8066 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL273883 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL8327 | DEMETHYL-CANTHARIDIN | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL8157 | — | IC50 | = | 300000.0 | nM | - |