Compound Detail
CHEMBL8066
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Basic Information
| ChEMBL ID | CHEMBL8066 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DHZBEENLJMYSHQ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
196.2
MW (Da)
0.64
ALogP
4
HBA
0
HBD
52.6
PSA (Ų)
0.42
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 8.4 | 8.4 | 4.0 | 1 |
| Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform CHEMBL3557 | IC50 | 5.1 | 5.1 | 8000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 4.0 | nM | 8.4 | Compound was tested for inhibition of specific [3H]cantharidin binding to CBP: R... | - |
| Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | IC50 | = | 8000.0 | nM | 5.1 | Compound was tested for inhibitory concentration of Protein Phosphatase 2A (PP2A... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(96)00166-7 | Unchecked | 3 |
| - | 10.1016/0960-894X(96)00166-7 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | 1 |
Data from ChEMBL 36 via Core Engine