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Assay Detail

CHEMBL767018

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested against S2-binding site of HIV-2 protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human immunodeficiency virus 2
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Human rhinovirus A protease (CHEMBL2857)
Type SINGLE PROTEIN
Organism Human rhinovirus sp.

Publication

Cyclic sulfolanes as novel and high affinity P2 ligands for HIV-1 protease inhibitors.
Ghosh AK, Thompson WJ, Lee HY, McKee SP, Munson PM, Duong TT, Darke PL, Zugay JA, Emini EA, Schleif WA.
J Med Chem (1993) 36 : 924 -927
PubMed 8464047 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.77 7.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL18067 1 7.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL18067 IC50 = 17.0 nM 7.77