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Assay Detail

CHEMBL767178

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for the inhibition of HIV-1 induced CPE (HTLV-III B strain ) peripheral blood lymphocytes (PBL).
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Thiadiazole derivatives: highly potent and specific HIV-1 reverse transcriptase inhibitors.
Hanasaki Y, Watanabe H, Katsuura K, Takayama H, Shirakawa S, Yamaguchi K, Sakai S, Ijichi K, Fujiwara M, Konno K.
J Med Chem (1995) 38 : 2038 -2040
PubMed 7540208 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.40 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL60314 1 8.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL60314 EC50 = 4.0 nM 8.40