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Assay Detail

CHEMBL767190

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was tested for cytotoxicity against HIV-1WEJO mock-infected PBL cells.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Meleagris gallopavo
Cell Type PBL
Confidence 1 — Organism
Curated By Autocuration

Publication

Synthesis and biological evaluation of certain alkenyldiarylmethanes as anti-HIV-1 agents which act as non-nucleoside reverse transcriptase inhibitors.
Cushman M, Golebiewski WM, Graham L, Turpin JA, Rice WG, Fliakas-Boltz V, Buckheit RW.
J Med Chem (1996) 39 : 3217 -3227
PubMed 8759644 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.18 5.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL109573 1 5.18

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL109573 EC50 = 6600.0 nM 5.18