Assay Detail
Binding
CHEMBL767316
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Inhibitory concentration against Protein phosphatase 1(10 nM) isolated from rabbit muscle
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Tissue | Muscle tissue |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Importance of the C28-C38 hydrophobic domain of okadaic acid for potent inhibition of protein serine-threonine phosphatases 1 and 2A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.47 | 6.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL280487 | OKADAIC ACID | — | 1 | 6.90 |
| CHEMBL2368224 | — | — | 1 | 4.03 |
| CHEMBL158922 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL280487 | OKADAIC ACID | IC50 | = | 126.0 | nM | 6.90 |
| CHEMBL2368224 | — | IC50 | = | 94000.0 | nM | 4.03 |
| CHEMBL158922 | — | IC50 | > | 1000000.0 | nM | - |