Assay Detail
Binding
CHEMBL767329
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Inhibitory concentration against protein phosphatase 1 was determined
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 1 (CHEMBL335) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.41 | 5.53 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL48076 | — | — | 1 | 5.53 |
| CHEMBL48449 | CANTHARIDIN | 4.0 | 1 | 5.44 |
| CHEMBL47665 | — | — | 1 | 5.33 |
| CHEMBL48010 | — | — | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL48076 | — | IC50 | = | 2960.0 | nM | 5.53 |
| CHEMBL48449 | CANTHARIDIN | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL47665 | — | IC50 | = | 4710.0 | nM | 5.33 |
| CHEMBL48010 | — | IC50 | = | 4820.0 | nM | 5.32 |