Assay Detail
Binding
CHEMBL767397
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Inhibition of human protein kinase C eta
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Ring size effect in the PKC inhibitory activities of perhydroazepine analogs of balanol
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.92 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL52529 | — | — | 1 | 9.22 |
| CHEMBL59828 | — | — | 1 | 8.40 |
| CHEMBL60254 | BALANOL | — | 1 | 7.66 |
| CHEMBL304549 | — | — | 1 | 7.22 |
| CHEMBL67442 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL52529 | — | IC50 | = | 0.6 | nM | 9.22 |
| CHEMBL59828 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL60254 | BALANOL | IC50 | = | 22.0 | nM | 7.66 |
| CHEMBL304549 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL67442 | — | IC50 | = | 80.0 | nM | 7.10 |