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Assay Detail

CHEMBL767398

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of [3H]- PDBu binding to peptide D of mouse skin Protein kinase C eta
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Protein kinase C eta type (CHEMBL4992)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Synthesis and characterization of the second cysteine-rich region of mouse skin PKCGh
Irie K, Yanai Y, Ohigashi H, Wender PA, Miller BL
Bioorg Med Chem Lett (1996) 6 : 353 -356
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 8.88 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL417692 1 10.00
CHEMBL27768 1 9.22
CHEMBL120645 1 8.47
CHEMBL24609 MONOCTANOIN COMPONENT C -1.0 1 7.84

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL417692 Ki = 0.1 nM 10.00
CHEMBL27768 Ki = 0.6 nM 9.22
CHEMBL120645 Ki = 3.36 nM 8.47
CHEMBL24609 MONOCTANOIN COMPONENT C Ki = 14.5 nM 7.84