Assay Detail
Binding
CHEMBL767437
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Inhibitory activity against protein kinase C.
32
Total Activities
32
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Novel IKK inhibitors: beta-carbolines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 32 | 4.82 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL310975 | — | — | 1 | 4.82 |
| CHEMBL311201 | — | — | 1 | - |
| CHEMBL309953 | — | — | 1 | - |
| CHEMBL275224 | NORHARMANE | — | 1 | - |
| CHEMBL312698 | — | — | 1 | - |
| CHEMBL79004 | — | — | 1 | - |
| CHEMBL312648 | — | — | 1 | - |
| CHEMBL82137 | — | — | 1 | - |
| CHEMBL78862 | — | — | 1 | - |
| CHEMBL80843 | — | — | 1 | - |
| CHEMBL81603 | — | — | 1 | - |
| CHEMBL312651 | — | — | 1 | - |
| CHEMBL312676 | — | — | 1 | - |
| CHEMBL310179 | — | — | 1 | - |
| CHEMBL80121 | — | — | 1 | - |
| CHEMBL78464 | — | — | 1 | - |
| CHEMBL81838 | — | — | 1 | - |
| CHEMBL81169 | — | — | 1 | - |
| CHEMBL82136 | — | — | 1 | - |
| CHEMBL309265 | — | — | 1 | - |
| CHEMBL78618 | — | — | 1 | - |
| CHEMBL80619 | — | — | 1 | - |
| CHEMBL78885 | — | — | 1 | - |
| CHEMBL81229 | — | — | 1 | - |
| CHEMBL78917 | — | — | 1 | - |
| CHEMBL81315 | — | — | 1 | - |
| CHEMBL312170 | — | — | 1 | - |
| CHEMBL81214 | — | — | 1 | - |
| CHEMBL81809 | — | — | 1 | - |
| CHEMBL311306 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL310975 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL82137 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL80121 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL310179 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL312676 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL312651 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL81603 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL80843 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL78862 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL78464 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL312648 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL79004 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL312698 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL275224 | NORHARMANE | IC50 | > | 25000.0 | nM | - |
| CHEMBL309953 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL81170 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL80793 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL311201 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL81838 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL81169 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL82136 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL309265 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL78618 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL80619 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL78885 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL81229 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL78917 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL81315 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL312170 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL81214 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL81809 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL311306 | — | IC50 | > | 25000.0 | nM | - |