Assay Detail
Binding
CHEMBL767486
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Observed inhibition activity against protein phosphatase 1 (PP1)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 1 (CHEMBL335) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A model for binding of structurally diverse natural product inhibitors of protein phosphatases PP1 and PP2A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.15 | 9.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4524071 | — | — | 1 | 9.38 |
| CHEMBL280487 | OKADAIC ACID | — | 1 | 8.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4524071 | — | IC50 | = | 0.42 | nM | 9.38 |
| CHEMBL280487 | OKADAIC ACID | IC50 | = | 1.24 | nM | 8.91 |