Assay Detail
Binding
CHEMBL767491
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Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes (BCLM)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Prostaglandin photoaffinity probes: synthesis and biological activity of azide-substituted 16-phenoxy- and 17-phenyl-PGF2 alpha prostaglandins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.34 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL815 | DINOPROST | 4.0 | 1 | 6.85 |
| CHEMBL88974 | — | — | 1 | 5.16 |
| CHEMBL90450 | — | — | 1 | 5.16 |
| CHEMBL2114224 | — | — | 1 | 4.17 |
| CHEMBL315519 | — | — | 1 | - |
| CHEMBL422418 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL815 | DINOPROST | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL88974 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL90450 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL2114224 | — | IC50 | = | 68000.0 | nM | 4.17 |
| CHEMBL315519 | — | IC50 | = | 220000.0 | nM | - |
| CHEMBL422418 | — | IC50 | = | 120000.0 | nM | - |