Assay Detail
Binding
CHEMBL767506
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In vitro inhibition of Prostaglandin G/H synthase from human polymorphs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Acetohydroxamic acids as potent, selective, orally active 5-lipoxygenase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.15 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL314360 | — | — | 1 | 5.50 |
| CHEMBL146730 | — | — | 1 | 5.30 |
| CHEMBL61608 | — | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL314360 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL146730 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL61608 | — | IC50 | = | 22000.0 | nM | 4.66 |