Assay Detail
Functional
CHEMBL767674
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Compound was tested for in vitro inhibition against human PMNL.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Modulators of leukotriene biosynthesis and receptor activation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.30 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL59356 | ATRELEUTON | 2.0 | 1 | 7.64 |
| CHEMBL90552 | — | — | 1 | 7.60 |
| CHEMBL88712 | VELIFLAPON | 3.0 | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL59356 | ATRELEUTON | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL90552 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL88712 | VELIFLAPON | IC50 | = | 220.0 | nM | 6.66 |