Assay Detail
Binding
CHEMBL767826
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and activity of a new methoxytetrahydropyran derivative as dual cyclooxygenase-2/5-lipoxygenase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.16 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL348825 | — | — | 1 | 5.89 |
| CHEMBL349370 | — | — | 1 | 4.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL348825 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL349370 | — | IC50 | = | 38000.0 | nM | 4.42 |