Assay Detail
Binding
CHEMBL767977
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Inhibition of guinea pig Phosphodiesterase
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antiinflammatory activity of a series of substituted 2,3-dihydro-6-hydroxypyrimido[2,1-f]purine-4,8(1H,9H)-diones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.48 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1370561 | AMINOPHYLLINE | 4.0 | 1 | 4.52 |
| CHEMBL14433 | — | — | 2 | 4.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1370561 | AMINOPHYLLINE | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL14433 | — | IC50 | = | 37000.0 | nM | 4.43 |
| CHEMBL14433 | — | IC50 | = | 200000.0 | nM | - |