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Assay Detail

CHEMBL768068

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro concentration required to inhibit the rate of human platelet aggregation (in platelet rich plasma) by 50% was determined in presence of 10 ug/mL of collagen
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Tissue Plasma
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Non-peptide fibrinogen receptor antagonists. 7. Design and synthesis of a potent, orally active fibrinogen receptor antagonist.
Duggan ME, Naylor-Olsen AM, Perkins JJ, Anderson PS, Chang CT, Cook JJ, Gould RJ, Ihle NC, Hartman GD, Lynch JJ.
J Med Chem (1995) 38 : 3332 -3341
PubMed 7650686 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.17 4.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL48371 1 4.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL48371 IC50 = 67000.0 nM 4.17