Assay Detail
Binding
CHEMBL768409
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The compound was tested in vitro for the inhibitory activity against LAR (human Protein-tyrosine phosphatase F)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Receptor-type tyrosine-protein phosphatase F (CHEMBL3521) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
PTP1B inhibition and antihyperglycemic activity in the ob/ob mouse model of novel 11-arylbenzo[b]naphtho[2,3-d]furans and 11-arylbenzo[b]naphtho[2,3-d]thiophenes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.10 | 6.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL324232 | — | — | 1 | 6.38 |
| CHEMBL108721 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL324232 | — | IC50 | = | 420.0 | nM | 6.38 |
| CHEMBL108721 | — | IC50 | = | 1500.0 | nM | 5.82 |