Assay Detail
Binding
CHEMBL768527
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Compound was tested for inhibition of Protein tyrosine phosphatase (PTP1B)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of novel PTP1b inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 4.30 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL129040 | — | — | 1 | 4.60 |
| CHEMBL274794 | 2-PYRIDINECARBOXALDEHYDE | — | 1 | 4.00 |
| CHEMBL440161 | DIHYDROCINNAMALDEHYDE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL129040 | — | Kd | = | 25000.0 | nM | 4.60 |
| CHEMBL274794 | 2-PYRIDINECARBOXALDEHYDE | Kd | = | 100000.0 | nM | 4.00 |
| CHEMBL440161 | DIHYDROCINNAMALDEHYDE | Kd | = | 150000.0 | nM | - |