Compound Detail
CHEMBL274794
2-PYRIDINECARBOXALDEHYDE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL274794 |
| Name | 2-PYRIDINECARBOXALDEHYDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CSDSSGBPEUDDEE-UHFFFAOYSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
107.1
MW (Da)
0.89
ALogP
2
HBA
0
HBD
30.0
PSA (Ų)
0.50
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.15
Kd 1 meas. best 4.0
Target Activity Profile
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| B16-F10 | IC50 | = | 70740.0 | nM | 4.15 | Cytotoxicity against mouse B16F10 cells assessed as reduction in cell viability | 30594028 |
| Unchecked | Kd | = | 100000.0 | nM | 4.0 | Compound was tested for inhibition of Protein tyrosine phosphatase (PTP1B) | 14698165 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22769561 | 10.1021/jf302075w | Meloidogyne incognita | 3 |
| 14698165 | 10.1016/j.bmcl.2003.10.058 | Unchecked | 2 |
| 6127411 | 10.1021/jm00351a015 | GABA-A receptor; anion channel | 1 |
| 31097402 | 10.1016/j.bmc.2019.05.001 | Sodium- and chloride-dependent GABA transporter 1 | 1 |
| 30777661 | 10.1016/j.bmc.2019.02.015 | Sodium- and chloride-dependent GABA transporter 1 | 1 |
| 30594028 | 10.1016/j.ejmech.2018.11.026 | B16-F10 | 1 |
Data from ChEMBL 36 via Core Engine