Assay Detail
Functional
CHEMBL768543
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity for relative cell viability compared to untreated control in Primary leukemic cells(PLC) by MTT assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Gallus gallus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel cationic transport agents for oligonucleotide delivery into primary leukemic cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.06 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL407898 | — | — | 1 | 5.38 |
| CHEMBL542389 | — | — | 1 | 5.07 |
| CHEMBL441617 | — | — | 1 | 5.07 |
| CHEMBL385213 | — | — | 1 | 4.92 |
| CHEMBL294514 | — | — | 1 | 4.85 |
| CHEMBL63095 | — | — | 1 | - |
| CHEMBL216608 | — | — | 1 | - |
| CHEMBL65606 | TMPYP4 | — | 1 | - |
| CHEMBL64170 | — | — | 1 | - |
| CHEMBL410693 | — | — | 1 | - |
| CHEMBL64624 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL407898 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL542389 | — | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL441617 | — | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL385213 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL294514 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL63095 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL216608 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL65606 | TMPYP4 | IC50 | > | 20000.0 | nM | - |
| CHEMBL64170 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL410693 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL64624 | — | IC50 | > | 20000.0 | nM | - |