Assay Detail
Binding
CHEMBL768820
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human progesterone in T47D human breast cancer cell
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Development of progesterone receptor antagonists from 1,2-dihydrochromeno[3,4-f]quinoline agonist pharmacophore.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.68 | 7.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL418684 | — | — | 1 | 7.07 |
| CHEMBL303293 | — | — | 1 | 6.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL418684 | — | IC50 | = | 86.0 | nM | 7.07 |
| CHEMBL303293 | — | IC50 | = | 514.0 | nM | 6.29 |