Assay Detail
Binding
CHEMBL769093
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Binding of Indolactam-V(ILV) to mutant Protein kinase C delta C1b domain (Tyr8 to Gly)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Probing the binding of indolactam-V to protein kinase C through site-directed mutagenesis and computational docking simulations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.96 | 7.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL116437 | — | — | 1 | 7.74 |
| CHEMBL27266 | INDOLACTUM | — | 1 | 6.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL116437 | — | Ki | = | 18.4 | nM | 7.74 |
| CHEMBL27266 | INDOLACTUM | Ki | = | 658.0 | nM | 6.18 |