Assay Detail
Binding
CHEMBL769329
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Proto-oncogene tyrosine-protein kinase Kit
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Mast/stem cell growth factor receptor Kit (CHEMBL1936) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of a new chemical class of potent angiogenesis inhibitors based on conformational considerations and database searching.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.38 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL101683 | — | — | 1 | 6.62 |
| CHEMBL101253 | VATALANIB | 3.0 | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL101683 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL101253 | VATALANIB | IC50 | = | 730.0 | nM | 6.14 |