Assay Detail
Binding
CHEMBL769615
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Displacement of phorbol 12,13-dibutyrate (PDBU) from recombinant Protein kinase C alpha
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and protein kinase C binding activity of benzolactam-V7.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.74 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27266 | INDOLACTUM | — | 1 | 7.96 |
| CHEMBL6453 | — | — | 1 | 7.82 |
| CHEMBL267144 | — | — | 1 | 6.48 |
| CHEMBL28567 | — | — | 1 | 4.68 |
| CHEMBL283673 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27266 | INDOLACTUM | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL6453 | — | Ki | = | 15.0 | nM | 7.82 |
| CHEMBL267144 | — | Ki | = | 334.0 | nM | 6.48 |
| CHEMBL28567 | — | Ki | = | 21000.0 | nM | 4.68 |
| CHEMBL283673 | — | Ki | = | 127000.0 | nM | - |