Assay Detail
Binding
CHEMBL770118
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against Yersinia Protein-tyrosine phosphatase 1B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Yersinia enterocolitica |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 1 (CHEMBL335) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
alpha-Ketocarboxylic acid-based inhibitors of protein tyrosine phosphatases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.85 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL57974 | — | — | 1 | 5.60 |
| CHEMBL299446 | — | — | 1 | 4.10 |
| CHEMBL60857 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL57974 | — | Ki | = | 2500.0 | nM | 5.60 |
| CHEMBL299446 | — | Ki | = | 79000.0 | nM | 4.10 |
| CHEMBL60857 | — | Ki | = | 179000.0 | nM | - |