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Assay Detail

CHEMBL770170

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against HIV-2 ROD strain in protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human immunodeficiency virus 2
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Human rhinovirus A protease (CHEMBL2857)
Type SINGLE PROTEIN
Organism Human rhinovirus sp.

Publication

Potent HIV protease inhibitors containing a novel (hydroxyethyl)amide isostere.
Beaulieu PL, Wernic D, Abraham A, Anderson PC, Bogri T, Bousquet Y, Croteau G, Guse I, Lamarre D, Liard F, Paris W, Thibeault D, Pav S, Tong L.
J Med Chem (1997) 40 : 2164 -2176
PubMed 9216835 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.89 9.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL13134 PALINAVIR 2.0 1 9.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL13134 PALINAVIR Ki = 0.13 nM 9.89