Assay Detail
Binding
CHEMBL770275
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]- PDBu from Protein kinase C delta C1b domain
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Structural basis of RasGRP binding to high-affinity PKC ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.53 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285801 | — | — | 1 | 10.00 |
| CHEMBL27266 | INDOLACTUM | — | 1 | 8.70 |
| CHEMBL6453 | — | — | 1 | 7.97 |
| CHEMBL7078 | — | — | 1 | 7.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285801 | — | Ki | = | 0.1 | nM | 10.00 |
| CHEMBL27266 | INDOLACTUM | Ki | = | 2.01 | nM | 8.70 |
| CHEMBL6453 | — | Ki | = | 10.7 | nM | 7.97 |
| CHEMBL7078 | — | Ki | = | 35.1 | nM | 7.46 |