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Assay Detail

CHEMBL771556

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Effective concentration against human rhinovirus 3C protease.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human rhinovirus sp.
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Human rhinovirus A protease (CHEMBL2857)
Type SINGLE PROTEIN
Organism Human rhinovirus sp.

Publication

Protease inhibitors: current status and future prospects.
Leung D, Abbenante G, Fairlie DP.
J Med Chem (2000) 43 : 305 -341
PubMed 10669559 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 7.78 8.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL20210 RUPINTRIVIR 2.0 1 8.30
CHEMBL95145 1 7.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL20210 RUPINTRIVIR EC50 = 5.0 nM 8.30
CHEMBL95145 EC50 = 56.0 nM 7.25