Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL771796

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity was measured against HRV-2 3C protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human rhinovirus sp.
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Human rhinovirus A protease (CHEMBL2857)
Type SINGLE PROTEIN
Organism Human rhinovirus sp.

Publication

Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements.
Webber SE, Okano K, Little TL, Reich SH, Xin Y, Fuhrman SA, Matthews DA, Love RA, Hendrickson TF, Patick AK, Meador JW, Ferre RA, Brown EL, Ford CE, Binford SL, Worland ST.
J Med Chem (1998) 41 : 2786 -2805
PubMed 9667969 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL95007 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL95007 Ki = 69.0 nM 7.16