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Assay Detail

CHEMBL772760

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Binding
Tested for the binding affinity against HIV-2 Protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human immunodeficiency virus 2
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Human rhinovirus A protease (CHEMBL2857)
Type SINGLE PROTEIN
Organism Human rhinovirus sp.

Publication

Structure-based design of HIV protease inhibitors: 4-hydroxycoumarins and 4-hydroxy-2-pyrones as non-peptidic inhibitors.
Thaisrivongs S, Tomich PK, Watenpaugh KD, Chong KT, Howe WJ, Yang CP, Strohbach JW, Turner SR, McGrath JP, Bohanon MJ.
J Med Chem (1994) 37 : 3200 -3204
PubMed 7932546 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.50 7.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL22164 1 7.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL22164 Ki = 32.0 nM 7.50