Assay Detail
Binding
CHEMBL772934
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Inhibitory concentration against Protease
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepacivirus hominis |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Protease inhibitors: current status and future prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.62 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL417559 | — | — | 1 | 7.30 |
| CHEMBL2370475 | — | — | 1 | 6.19 |
| CHEMBL444807 | — | — | 1 | 5.50 |
| CHEMBL2370476 | — | — | 1 | 5.40 |
| CHEMBL115114 | — | — | 1 | 5.21 |
| CHEMBL325640 | — | — | 1 | 5.19 |
| CHEMBL295605 | — | — | 1 | 4.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL417559 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL2370475 | — | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL444807 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL2370476 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL115114 | — | IC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL325640 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL295605 | — | IC50 | = | 28000.0 | nM | 4.55 |