Assay Detail
Functional
CHEMBL779261
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for its ability to stimulate amylase secretion from rat pancreatic acini
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
On the significance of the C-terminal primary amide in cholecystokinin
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 6.82 | 10.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL384035 | — | — | 1 | 10.30 |
| CHEMBL384505 | — | — | 2 | 7.52 |
| CHEMBL265147 | — | — | 1 | 7.50 |
| CHEMBL436690 | — | — | 1 | 6.16 |
| CHEMBL268337 | — | — | 1 | 5.03 |
| CHEMBL414523 | — | — | 1 | 4.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL384035 | — | EC50 | = | 0.05 | nM | 10.30 |
| CHEMBL384505 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL265147 | — | EC50 | = | 32.0 | nM | 7.50 |
| CHEMBL384505 | — | EC50 | = | 70.0 | nM | 7.16 |
| CHEMBL436690 | — | EC50 | = | 700.0 | nM | 6.16 |
| CHEMBL268337 | — | EC50 | = | 9300.0 | nM | 5.03 |
| CHEMBL414523 | — | EC50 | = | 86000.0 | nM | 4.07 |