Assay Detail
Functional
CHEMBL779297
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In vitro inhibition of microsomal lipid peroxidation
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.49 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL101831 | — | — | 1 | 5.57 |
| CHEMBL101229 | — | — | 1 | 5.55 |
| CHEMBL101025 | — | — | 1 | 5.52 |
| CHEMBL316638 | — | — | 1 | 5.32 |
| CHEMBL100690 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL101831 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL101229 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL101025 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL316638 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL100690 | — | IC50 | > | 10000.0 | nM | - |