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Assay Detail

CHEMBL779514

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Functional
Inhibition of thrombin-induced blood platelet aggregation in rat
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Cyclic guanidines. 14. Imidazo[1,2-a]thienopyrimidin-2-one derivatives as blood platelet aggregation inhibitors.
Ishikawa F, Kosasayama A, Yamaguchi H, Watanabe Y, Saegusa J, Shibamura S, Sakuma K, Ashida S, Abiko Y.
J Med Chem (1981) 24 : 376 -382
PubMed 7265124 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL552955 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL552955 EC50 = 3000.0 nM 5.52