Assay Detail
Functional
CHEMBL779555
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In vitro inhibitory activity was evaluated against rat squalence epoxidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.52 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL537176 | — | — | 1 | 7.60 |
| CHEMBL27885 | — | — | 1 | 7.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL537176 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL27885 | — | IC50 | = | 36.0 | nM | 7.44 |