Assay Detail
Functional
CHEMBL779598
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Calcium channel blocking activity in K+ stimulated rat aorta assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Enantiodifferentiation of dihydropyridine PAF antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.89 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL105029 | — | — | 1 | 7.92 |
| CHEMBL53019 | — | — | 1 | 7.85 |
| CHEMBL319839 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL105029 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL53019 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL319839 | — | IC50 | > | 1000.0 | nM | - |