Assay Detail
Functional
CHEMBL779972
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration for relaxation of isolated rat aortic strips, submaximally contracted with phenylephrine at 0.1 uM was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Neuroprotection against ischemic brain injury conferred by a novel nitrate ester.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.72 | 5.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL730 | NITROGLYCERIN | 4.0 | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL730 | NITROGLYCERIN | EC50 | = | 1900.0 | nM | 5.72 |