Assay Detail
Functional
CHEMBL779975
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration of compound that can stimulate phosphoinositol metabolism in rat hippocampus
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Hippocampus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and neurochemical evaluation of 5-(3-alkyl-1,2,4- oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidines as M1 muscarinic receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.98 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL277014 | — | — | 1 | 5.28 |
| CHEMBL20835 | ACECLIDINE | 3.0 | 1 | 4.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL277014 | — | EC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL20835 | ACECLIDINE | EC50 | = | 21000.0 | nM | 4.68 |