Assay Detail
Functional
CHEMBL780192
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its effect on the incorporation of [14C]- acetate into sterols measured rat spleen.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Spleen |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Relationship between tissue selectivity and lipophilicity for inhibitors of HMG-CoA reductase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.32 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2368089 | — | — | 1 | 8.05 |
| CHEMBL2368088 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2368089 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL2368088 | — | IC50 | = | 266.0 | nM | 6.58 |