Assay Detail
Functional
CHEMBL780340
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Compound was tested for its inhibitory activity against lipid peroxidation in rat brain homogenates.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Prodrug and covalent linker strategies for the solubilization of dual-action antioxidants/iron chelators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.72 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL96250 | — | — | 1 | 6.52 |
| CHEMBL70927 | DEFERIPRONE | 4.0 | 1 | 5.41 |
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | 2.0 | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL96250 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL70927 | DEFERIPRONE | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | IC50 | = | 5900.0 | nM | 5.23 |