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Assay Detail

CHEMBL780609

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro ability to inhibit antigen-induced release of histamine (AIR) from rat mast cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Synthesis and antiallergic activities of 1,3-oxazolo[4,5-h]quinolines.
Musser JH, Jones H, Sciortino S, Bailey K, Coutts SM, Khandwala A, Sonnino-Goldman P, Leibowitz M, Wolf P, Neiss ES.
J Med Chem (1985) 28 : 1255 -1259
PubMed 2411926 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL74 CROMOLYN SODIUM 4.0 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL74 CROMOLYN SODIUM IC50 = 3000.0 nM 5.52