Assay Detail
Functional
CHEMBL780692
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Ability of compound to stimulate in vitro amylase release from rat pancreatic acini
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological activity of some partially modified retro-inverso analogues of cholecystokinin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 7.71 | 10.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL384035 | — | — | 1 | 10.30 |
| CHEMBL1160501 | — | — | 1 | 8.22 |
| CHEMBL1160499 | — | — | 1 | 7.77 |
| CHEMBL1160500 | — | — | 1 | 7.52 |
| CHEMBL1160485 | — | — | 1 | 7.52 |
| CHEMBL1160486 | — | — | 1 | 6.89 |
| CHEMBL1160488 | — | — | 1 | 5.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL384035 | — | EC50 | = | 0.05 | nM | 10.30 |
| CHEMBL1160501 | — | EC50 | = | 6.0 | nM | 8.22 |
| CHEMBL1160499 | — | EC50 | = | 17.0 | nM | 7.77 |
| CHEMBL1160500 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL1160485 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL1160486 | — | EC50 | = | 130.0 | nM | 6.89 |
| CHEMBL1160488 | — | EC50 | = | 1700.0 | nM | 5.77 |